NSE antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human NSE, identical to the related Rabbit and rat sequences, as the immunogen
Optimal conditions to be determined by the end user
Storage & Safety
Storage
Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Enolase is an enzyme in the glycolysis system and the protein consists of a dimer structure selected from three subunits alpha, beta and gamma. As alpha-gamma and gamma-gamma enolase exists in neuron cell and axis cylinder processes, they are called ?Neuron specific Enolase (NSE)?. Recently, it appears that NSE exists in neuroendocrine cells found in internal organs, so it is known as a tumor marker which is useful for the study of small cell lung carcinoma, neuroblastoma and neuroendocrine tumors.