NT4 protein (30R-AN015)

Purified recombinant Human NT4 protein

Synonyms NT-4/NT-5 protein, NT-4, NT-4 protein, NT4, Neurotrophic 4/5 protein, NT4 protein, NT 4 protein, Neurotrophin-4 protein, NT 4
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of NT4 protein corresponding to amino acids GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 14.0 kDa
Form & Buffer Supplied lyophilized with no additives.

Usage & Assay Information

Bioactivity Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance NT-4 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and tr kb receptors and promotes the survival of peripheral sensory sympathetic neurons.

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Availability: In stock

Price: €211.69
Size: 10 ug
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