NXF1 antibody (70R-1323)

Rabbit polyclonal NXF1 antibody raised against the N terminal of NXF1

Synonyms Polyclonal NXF1 antibody, Anti-NXF1 antibody, NXF-1 antibody, NXF-1, NXF1, Nuclear Rna Export Factor 1 antibody, NXF 1, NXF 1 antibody
Specificity NXF1 antibody was raised against the N terminal of NXF1
Cross Reactivity Human
Applications IHC, WB
Immunogen NXF1 antibody was raised using the N terminal of NXF1 corresponding to a region with amino acids MADEGKSYSEHDDERVNFPQRKKKGRGPFRWKYGEGNRRSGRGGSGIRSS
Assay Information NXF1 Blocking Peptide, catalog no. 33R-5618, is also available for use as a blocking control in assays to test for specificity of this NXF1 antibody

Images

Western Blot analysis using NXF1 antibody (70R-1323)

NXF1 antibody (70R-1323) used at 1.25 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 68 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of NXF1 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.

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Images

  • Western Blot analysis using NXF1 antibody (70R-1323) | NXF1 antibody (70R-1323) used at 1.25 ug/ml to detect target protein.

Availability: In stock

Price: €258.73
Size: 100 ug
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