OTUB1 antibody (70R-12629)
Affinity purified Rabbit polyclonal OTUB1 antibody
Overview
Overview
| Synonyms | Polyclonal OTUB1 antibody, Anti-OTUB1 antibody, MGC111158 antibody, ubiquitin-specific-processing protease OTUB1 antibody, otubain-1 antibody, OTUB-1 antibody, ubiquitin thioesterase OTUB1 antibody, OTUB1 antibody, OTUB 1 antibody, FLJ20113 antibody, deubiquitinating enzyme OTUB1 antibody, ubiquitin-specific protease otubain 1 antibody, MGC4584 antibody, OTU1 antibody, OTUB 1, OTUB1, FLJ40710 antibody, OTUB-1, OTB1 antibody, OTU domain-containing ubiquitin aldehyde-binding protein 1 antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | ICC, IF, WB |
| Immunogen | OTUB1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 149 of OTUB1 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | OTUB1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 31 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 1X PBS, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.25 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. |
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