p53 antibody (10R-8113)
Mouse monoclonal p53 antibody
Overview
Overview
| Synonyms | Monoclonal p53 antibody, Anti-p53 antibody, p53 Oncoprotein antibody, p53, BCC7 antibody, BOS_18908 antibody, brp53 antibody, cellular tumor antigen p53 antibody, drp53 antibody, EGK_08142 antibody, etID22686.5 antibody, fb40d06 antibody, LFS1 antibody, Li-Fraumeni syndrome antibody, p53 antibody, p53 tumor suppressor antibody, p53 tumor suppressor phosphoprotein antibody, phosphoprotein p53 antibody, transformation related protein 53 antibody, transformation-related protein 53 antibody, trp53 antibody, tumor protein 53 antibody, tumor protein p53 (Li-Fraumeni syndrome) antibody, tumor suppressing protein antibody, tumor suppressor homolog p53 antibody, Tumor suppressor p53 antibody, tumor suppressor protein antibody, tumor suppressor protein p53 antibody, tumor suppressor TP53 antibody, tumor supressor p53 antibody, Xp53 antibody |
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| Specificity | Specific for human p53 and recognizes amino acid sequence 16-25 |
| Cross Reactivity | Human |
| Applications | FC, IHC, IHC-F, IHC-P, WB |
| Immunogen | p53 antibody was raised in Mouse using recombinant human wild-type p53 protein as the immunogen. |
Specifications
| Host | Mouse |
|---|---|
| Clone | Bp53.12 |
| Isotype | IgG2a |
| Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage & Assay Information
| Usage Recommendations | FC: 1:25-1:200, IHC: 1:25-1:200, WB: 1:100-1:1000 |
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General Information
| Biological Significance | p53 is a 53 kD protein that forms tetramers and functions as a tumor suppressor and transcriptional activator of genes that inhibit growth and/or invasion, cell cycle checkpoint after irradiation, DNA repair, apoptotic induction, signal transduction, and cell adhesion. This protein is localized to the nucleus when activated and can be upregulated by genotoxic or other cellular stresses. |
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