PARP1 antibody (70R-49343)
Purified Polyclonal PARP1 antibody
Overview
Overview
| Synonyms | Polyclonal PARP1 antibody, Anti-PARP1 antibody, ADPRT antibody, PPOL antibody, Poly [ADP-ribose] polymerase 1 antibody, PARP-1 antibody, ADP-ribosyltransferase diphtheria toxin-like 1 antibody, ARTD1 antibody, NAD(+) ADP-ribosyltransferase 1 antibody, ADPRT 1 antibody, Poly[ADP-ribose] synthase 1 antibody |
|---|---|
| Specificity | Recognizes endogenous levels of PARP1 protein |
| Cross Reactivity | Mouse, Rat |
| Applications | WB |
| Immunogen | PARP1 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PARP1 as the immunogen |
Images
Western blot analysis using PARP1 antibody (70R-49343)
Western blot analysis of PARP1 expression in MCF7 colchicine-treated (A); Raw264.7 colchicine-treated (B); rat brain (C) whole cell lysates.
Specifications
| Host | Rabbit |
|---|---|
| Method of Purification | PARP1 antibody was purified by immunogen affinity chromatography |
| Form & Buffer | Supplied in liquid form in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3 with 30% glycerol and 0.01% sodium azide |
Usage & Assay Information
| Usage Recommendations | WB: 1:500 - 1:1000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term, aliquot and store at -20 deg C. Avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | PARP1 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. |
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