PDCD12 antibody (10R-1111)

Mouse monoclonal PDCD12 antibody

Synonyms Monoclonal PDCD12 antibody, Anti-PDCD12 antibody, PDCD-12 antibody, programmed cell death 12 antibody, cell death regulator aven antibody, PDCD12, caspase activation inhibitor antibody, PDCD 12 antibody, PDCD-12, PDCD 12, PDCD12 antibody, apoptosis antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, IHC, WB
Immunogen PDCD12 antibody was raised in mouse using recombinant human PDCD12 (254-362aa) purified from E. coli as the immunogen.

Images

Western Blot analysis of PDCD12 antibody (10R-1111)

The extracts of mouse kidney (50 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Host Mouse
Clone 3G4
Isotype IgG2a kappa
Source Anti-human PDCD12 antibody, clone 3G4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PDCD12 protein.
Method of Purification PDCD12 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PDCD12 (Programmed cell death 12), also referred to as AVEN, represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein that blocks apoptosis impeded by Apaf-1 mediated caspase activation. Bcl-2 and BAD also interact with PDCD12 to prevent apoptosis. It is expressed in a wide variety of normal tissues including heart, skeletal muscle, kidney, liver, testis, and diseases such as cancer

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Images

  • Western Blot analysis of PDCD12 antibody (10R-1111) | The extracts of mouse kidney (50 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Availability: In stock

Price: €249.33
Size: 100 ul
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