PDGF Receptor alpha antibody (20R-PR008)

Rabbit polyclonal PDGF Receptor alpha antibody

Synonyms Polyclonal PDGF Receptor alpha antibody, Anti-PDGF Receptor alpha antibody, Platelet Derived Growth Factor Receptor alpha antibody, PDGFRB antibody, PDGFR alpha antibody
Specificity Human
Cross Reactivity Mouse
Applications IP, WB
Immunogen PDGF receptor alpha antibody was raised in rabbit using peptide corresponding to amino acids 1035-1053 (C-GKRNRHSSQTSEESAIETG) of human PDGF Receptor slpha as the immunogen.

Images

Western blot analysis using PDGF Receptor alpha antibody (20R-PR008)

Western blot analysis of 3T3/NIH cell lysate probed with Anti-PDGF Receptor alpha (1:500 dilution).

Specifications

Host Rabbit
Isotype IgG
Method of Purification PDGF Receptor alpha antibody was purified by affinity chromatography.
Molecular Weight 150-170 kDa (predicted detection band MW)
Form & Buffer Immunoaffinity purified rabbit IgG supplied in in 70% storage buffer( 0.2 M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% Sodium Azide) and 30% glycerol.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

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Images

  • Western blot analysis using PDGF Receptor alpha antibody (20R-PR008) | Western blot analysis of 3T3/NIH cell lysate probed with Anti-PDGF Receptor alpha (1:500 dilution).

Availability: In stock

Price: €399.86
Size: 200 ul
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