PDGF Receptor beta antibody (20R-PR009)
Rabbit polyclonal PDGF Receptor beta antibody
Overview
Overview
| Synonyms | Polyclonal PDGF Receptor beta antibody, Anti-PDGF Receptor beta antibody, PDGFRB antibody, PDGFR beta antibody, Platelet Derived Growth Factor Receptor beta antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | Mouse |
| Applications | ICC, IP, WB |
| Immunogen | PDGF receptor beta antibody was raised in rabbit using a synthetic peptide (QPNEGDNDYIIPLA) corresponding to amino acids 1013-1025 of human PDGF receptor beta as the immunogen. |
Images
Western blot analysis using PDGF Receptor beta antibody (20R-PR009)
Western blot analysis of NIH 3T3 cell lysate probed with Anti-PDGF Receptor beta
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Method of Purification | PDGF Receptor beta antibody was purified by Protein G chromatography. |
| Molecular Weight | 190 kDa (predicted detection band MW) |
| Form & Buffer | Frozen in 0.1M tris-glycine buffer, pH 7.4, with 0.15M NaCl, and 0.05% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. |
General Information
| Biological Significance | Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation. |
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