PDGFr antibody (20-PS28)
Sheep polyclonal PDGFr antibody
Overview
Overview
| Synonyms | Polyclonal PDGFr antibody, Anti-PDGFr antibody, Platelet-derived Growth Factor Receptor antibody |
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| Cross Reactivity | This antibody recognizes PDGFr |
| Applications | User optimized |
| Immunogen | PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen. |
Specifications
| Host | Sheep |
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| Form & Buffer | Purified by protein G chromatography and supplied in PBS with 0.05% NaN3. |
| Concentration | Typically 1-5 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation. |
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