PHB protein (His tag) (80R-2691)

Purified recombinant PHB protein (His tag)

Synonyms Prohibitin protein, PHB1 protein, PHB
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of PHB protein (His tag) (80R-2691)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-272 aa: MGSSHHHHHH SSGLVPRGSH MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV GEGTHFLIPW VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA SQLPRIFTSI GEDYDERVLP SITTEILKSV VARFDAGELI TQRELVSRQV SDDLTERAAT FGLILDDVSL THLTFGKEFT EAVEAKQVAQ QEAERARFVV EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK LEAAEDIAYQ LSRSRNITYL PAGQSVLLQL PQ
Expression System E.coli
Grade & Purity > 85% pure
Molecular Weight 31.9 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Concentration 1 mg/ml

Storage & Safety

Storage Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles

General Information

Biological Significance PHB is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. Recombinant human PHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • <div><font face=Calibri size=2>SDS-PAGE analysis of PHB protein (His tag) (80R-2691)</font></div>     | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €223.13
Size: 50 ug
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