PHGDH protein (His tag) (80-1603)

Purified recombinant PHGDH protein (His tag)

Synonyms 3 PGDH protein, D 3 phosphoglycerate dehydrogenase protein
Species Human

Specifications

Grade & Purity > 85% pure
Tag/Conjugate His tag
Form & Buffer Lyophilized, Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance PHGDH is induced by 17-beta-estradiol (estrogenic ligand) and 4-hydroxytamoxifen (agonist/antagonist ligand). It is positively regulated by the transcription factors SP1 and NF-Y.Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency). It is characterized by congenital microcephaly, psychomotor retardation, and seizures.

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Availability: In stock

Price: €1,099.39
Size: 50 ug
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