Phospho STAT3 antibody (20R-2918)
Rabbit polyclonal Phospho STAT3 antibody
Overview
Overview
| Synonyms | Polyclonal Phospho STAT3 antibody, Anti-Phospho STAT3 antibody, STAT3 antibody, signal transducer and activator of transcription 3 (acute-phase response factor) antibody, acute phase response factor antibody, acute-phase response factor antibody, APRF antibody, BOS_19088 antibody, DNA-binding protein APRF antibody, fc15d02 antibody, fl59g06 antibody, HIES antibody, RCJMB04_38l20 antibody, RP23-279L23.5 antibody, signal transducer and activator of transcription 3 antibody, signal transduction and activation of transcription 3 antibody, z-STAT3 antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | Phospho STAT3 antibody was raised in Rabbit using a synthetic target peptide as the immunogen |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | Phospho STAT3 antibody was purified by Protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1: 2000 |
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Storage & Safety
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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General Information
| Biological Significance | STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. |
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