PIM1 antibody (70R-12089)

Rabbit polyclonal PIM1 antibody

Synonyms Polyclonal PIM1 antibody, anti-PIM1 antibody, PIM1 antibody, PIM antibody, PIM-1 antibody, PIM-1 antibody, Proviral Integration Site 1 antibody, PIM-1, PIM 1 antibody, PIM1, PIM 1
Cross Reactivity Human, Mouse, Rat
Applications IP, WB
Immunogen PIM1 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 296 of rat PIM1 as the immunogen.
Assay Information PIM1 Blocking Peptide, catalog no. 33R-10916, is also available for use as a blocking control in assays to test for specificity of this PIM1 antibody

Images

Western Blot analysis using PIM1 antibody (70R-12089)

Western blot analysis of PIM1 using Jurkat cell lysate.

Specifications

Host Rabbit
Isotype IgG
Method of Purification PIM1 antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.5-4 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using PIM1 antibody (70R-12089)</font></div>     | Western blot analysis of PIM1 using Jurkat cell lysate.

Availability: In stock

Price: €282.21
Size: 100 ug
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