PKC gamma protein (30R-2876)

Purified recombinant Human PKC gamma protein

Synonyms PKC protein, protein kinase C protein, gamma kinase C protein
Species Human
Protein Type Recombinant

Specifications

Expression System Sf-9 insect cells
Grade & Purity > 80% pure
Method of Purification PKC gamma protein was purified using a a proprietary chromatographic technique.
Molecular Weight 105 kDa
Form & Buffer Supplied in a storage buffer consisting of 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF and 25% glycerol

Usage & Assay Information

Bioactivity The specific activity of PKC gammais approximately 512 nmol/min/mg

Storage & Safety

Storage Store at -80 deg C

General Information

Biological Significance PKC gamma is a member of the protein kinase C family of serine-and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKC is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKC and may thereby provide neuroprotection.

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Availability: In stock

Price: €347.65
Size: 5 ug
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