PKIB protein (His tag) (80R-1746)
Purified recombinant Human PKIB protein
|Synonyms||cAMP-dependent protein kinase inhibitor beta protein, FLJ23817 protein, PRKACN2 protein|
Coomassie Blue stained SDS-PAGE of PKIB protein (His tag) (80R-1746)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-78 amino acids: MGSSHHHHHH SSGLVPRGSH MRTDSSKMTD VESGVANFAS SARAGRRNAL PDIQSSAATD GTSDLPLKLE ALSVKEDAKE KDEKTTQDQL EKPQNEEK|
|Grade & Purity||> 90% pure|
|Molecular Weight||10.6 kDa (98aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||PKIB, also known as cAMP-dependent protein kinase inhibitor beta, is a member of the cAMP-dependent protein kinase inhibitor family. This protein may interact with the catalytic subunit of cAMP-dependent protein kinase and act as a competitive inhibitor. At least three alternatively spliced transcript variants encoding the same protein have been reported. Recombinant human PKIB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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