Plexin B2 antibody (10R-6531)
Armenian Hamster monoclonal Plexin B2 antibody
Overview
Overview
| Synonyms | Monoclonal Plexin B2 antibody, Anti-Plexin B2 antibody, Plexin B 2 antibody, Plexin B2, Plexin B-2, Plexin B 2, Plexin B-2 antibody, Plexin B2 antibody |
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| Applications | FC, IHC, IP, WB |
| Assay Information | A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest |
Images
Flow Cytometric analysis using Plexin B2 antibody (10R-6531)
Staining of the PDV cell line with 0.25 ug of Armenian Hamster IgG Isotype Control (open histogram) or 0.25 ug of Plexin-B2 antibody (filled histogram) followed by Anti-Armenian Hamster IgG (biotin) and Streptavidin (PE). Total viable cells were used for analysis.
Specifications
| Host | Hamster |
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| Clone | 3E7 |
| Isotype | IgG |
| Method of Purification | Plexin B2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | FC: = 0.5 ug/test |
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Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved coverting the single chain presursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized. |
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