PLP1 antibody (70R-10646)

Affinity purified Chicken polyclonal PLP1 antibody

Synonyms Polyclonal PLP1 antibody, Anti-PLP1 antibody, PLP antibody, SPG2 antibody, PLP-1, PLP1, MMPL antibody, PLP/DM20 antibody, Proteolipid Protein 1 antibody, PLP-1 antibody, PMD antibody, PLP 1 antibody, PLP 1
Applications ICC, IHC, WB
Immunogen PLP1 antibody was raised in Chicken using a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate corresponding to a region of the PLP gene product shared between the Human (NP_000524, PLP1 isoform 1 and PLP1 isoform 2 (NP_955772)] and Mouse (P6

Images

Immunofluorescent staining of PLP1 antibody (70R-10646)

In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.

Specifications

Host Chicken
Method of Purification PLP1 antibody was purified by affinity chromatography.
Form & Buffer Supplied in liquid form in 10 mM PBS buffer, pH 7.2, with 0.02% sodium azide added as a preservative.
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations ICC: 1:1000-1:2000; IHC: 1:1000-1:2000; WB: 1:2000-1:5000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. Protect from light.

General Information

Biological Significance PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.

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Images

  • Immunofluorescent staining of PLP1 antibody (70R-10646) | In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.

Availability: In stock

Price: €502.25
Size: 1 ml
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