Polymyxin B Sulfate (USP grade powder) (51R-U547007)
Polymyxin B Sulfate (USP grade powder) chemical reference substance
Specifications
| Form & Buffer | Supplied as a powder. |
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General Information
| Biological Significance | Polymyxins are antibiotics, with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. They are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria due to their specificity for the lipopolysaccharide molecule that exists within many Gram-negative outer membranes. |
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