PPIF protein (80R-4267)

Recombinant Rat PPIF protein with His tag

Synonyms Rat PPIF protein, Recombinant PPIF protein, Peptidyl-prolyl cis-trans isomerase F protein, mitochondrial protein, CyP-D protein, CypD protein, PPIase protein
Species Rat
Protein Type Recombinant
Applications Control, SDS-PAGE

Images

Coomassie blue stained SDS-PAGE showing analysis of PPIF protein(80R-4267)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 30-206 amino acids of Rat PPIF protein: MGSSHHHHHH SSGLVPRGSH MGSCSDGGAR GANSSSQNPL VYLDVGADGQ PLGRVVLELK ADVVPKTAEN FRALCTGEKG FGYKGSTFHR VIPAFMCQAG DFTNHNGTGG KSIYGSRFPD ENFTLKHVGP GVLSMANAGP NTNGSQFFIC TIKTDWLDGK HVVFGHVKEG MDVVKKIESF GSKSGKTSKK IVITDCGQLS
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 21.2Da
Tag/Conjugate His tag
Form & Buffer Supplied as liquid in PBS (pH 7.4) containing 10% glycerol and 1mM DTT
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles.

General Information

Biological Significance Ppif also known as Peptidyl-prolyl cis-trans isomerase F, mitochondrial. Ppif accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis the requirement of the PPIase activity for this function is debated. Recombinant rat Ppif was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

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Coomassie blue stained SDS-PAGE showing analysis of PPIF protein(80R-4267)



 | 

Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €377.91
Size: 50 ug
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