PPL antibody (20R-2607)

Guinea Pig polyclonal Periplakin antibody

Synonyms Polyclonal Periplakin antibody, Anti-Periplakin antibody, MGC134872 antibody, KIAA0568 antibody, PPL antibody
Specificity Human Periplakin
Cross Reactivity Bovine
Applications IHC, WB
Immunogen Periplakin antibody was raised in Guinea Pig using synthetic peptides of human periplakin coupled to KLH as the immunogen.

Specifications

Host Guinea Pig
Form & Buffer Supplied in liquid form. Contains 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:50-100, WB: 1:1000-2000

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Periplakin is a protein that in humans is encoded by the PPL gene. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments.

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