Presenilin 2 antibody (70R-13901)

Affinity purified Goat polyclonal Presenilin 2 antibody

Synonyms Polyclonal Presenilin 2 antibody, Anti-Presenilin 2 antibody, PS2 antibody, Presenilin-2 antibody, Presenilin -2, Presenilin 2, PS-2 antibody, Presenilin 2 antibody, Presenilin -2 antibody, Presenilin 2
Applications IHC-F, IHC-P, WB
Immunogen Presenilin 2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Presenilin-2, different from the related Rabbit and rat sequences by two amino acids, as the immunogen

Images

Immunohistochemical staining using Presenilin 2 antibody (70R-13901)

Immunohistochemistry of paraffin embedded section of Human Mammary Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification Presenilin 2 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.

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Images

  • Immunohistochemical staining using Presenilin 2 antibody (70R-13901) | Immunohistochemistry of paraffin embedded section of Human Mammary Cancer Tissue
  • Western blot analysis using Presenilin 2 antibody (70R-13901) | Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: MCF-7 Cell Lysate, Lane 4: HELA Cell Lysate, ,Lane 5: SMMC Cell Lysate, Lane 6: CEM Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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