Presenilin 2 antibody (70R-PG003)
Affinity purified Goat polyclonal Presenilin 2 antibody
Overview
Overview
| Synonyms | Polyclonal Presenilin 2 antibody, Anti-Presenilin 2 antibody, Presenilin-2 antibody, PS2 antibody, Presenilin -2, Presenilin 2, Presenilin 2, Presenilin -2 antibody, Presenilin 2 antibody, PS-2 antibody |
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| Applications | User optimized |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. |
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