PRKAB1 protein (His tag) (80R-2564)

Purified recombinant PRKAB1 protein

Synonyms PRKAB-1, PRKAB 1 protein, 5'-AMP-activated protein kinase subunit beta-1 protein, PRKAB1, HAMPKb protein, PRKAB 1, AMPK protein, PRKAB-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of PRKAB1 protein (His tag) (80R-2564)

SDS-PAGE gel analysis of PRKAB1 protein (His tag) where the figure is annotated with amount of protein run on the gel.

Specifications

Residues 1-270 aa: MGSSHHHHHH SSGLVPRGSH MGSMGNTSSE RAALERHGGH KTPRRDSSGG TKDGDRPKIL MDSPEDADLF HSEEIKAPEK EEFLAWQHDL EVNDKAPAQA RPTVFRWTGG GKEVYLSGSF NNWSKLPLTR SHNNFVAILD LPEGEHQYKF FVDGQWTHDP SEPIVTSQLG TVNNIIQVKK TDFEVFDALM VDSQKCSDVS ELSSSPPGPY HQEPYVCKPE ERFRAPPILP PHLLQVILNK DTGISCDPAL LPEPNHVMLN HLYALSIKDG VMVLSATHRY KKKYVTTLLY KPI
Expression System E.coli
Grade & Purity > 85% pure
Molecular Weight 32.8 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage, for long term storage aliquot and freeze at -20 deg C or -70 deg C

General Information

Biological Significance PRKAB1 inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

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Images

  • SDS-PAGE analysis of PRKAB1 protein (His tag) (80R-2564) | SDS-PAGE gel analysis of PRKAB1 protein (His tag) where the figure is annotated with amount of protein run on the gel.

Availability: In stock

Price: €269.12
Size: 10 ug
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