Monoclonal Pro-Collagen I antibody, Anti-Pro-Collagen I antibody, Pro Collagen I antibody, Pro-Collagen I antibody, Pro-Collagen 1 antibody, Pro-Collagen 1 antibody, Anti Pro-Collagen I antibody, Pro Collagen I antibody
Specificity
Human
Cross Reactivity
Bovine, guinea pig
Applications
IHC-P
Immunogen
Pro-Collagen I antibody was raised in mouse using human procollagen I as the immunogen.
Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
General Information
Biological Significance
Collagens are the major fibrillar components of most connective tissues. Collagens form a family of proteins, and each type has its own characteristic amino acid sequence. Interstitial collagens are synthesised and secreted out of cells as procollagens. During the secretion, carboxy- and aminoterminal propeptides are cleaved off from the parent molecule by specific proteases. This releases the collagen molecule, together with its respective procollagen propeptides, in stoichiometric amounts into the extracellular space.