Immunohistochemical staining using Prohibitin antibody (biotin) (61R-P140aBT)
Formalin-fixed, paraffin-embedded rat heart stained with Prohibitin antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of cardiac muscles
Prohibitin antibody (biotin)
Immunohistochemical staining using Prohibitin antibody (biotin) (61R-P140aBT)
Formalin-fixed, paraffin-embedded rat heart stained with Prohibitin antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of cardiac muscles
Immunohistochemical staining using Prohibitin antibody (biotin) (61R-P140aBT)
Formalin-fixed, paraffin-embedded human heart stained with Prohibitin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of cardiac muscle cells.
Specifications
Host
Mouse
Clone
II-14-10
Isotype
IgG1
Method of Purification
Prohibitin antibody (biotin) was purified by Protein G chromatography.
Tag/Conjugate
Biotin
Form & Buffer
Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
IHC-F/p: 2-4 ug/ml, IP: 2 ug/ml protein lysate,WB: 0.5-1 ug/ml
Storage & Safety
Storage
Store at 4 deg C.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
General Information
Biological Significance
Prohibitin is an evolutionarily conserved protein located in the inner membrane of mitochondria. PROHIBITIN APPEARS TO BE A VERY RELIABLE MARKER OF MITOCHONDRIA. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.