Proinsulin antibody (10-I30G)
Mouse monoclonal Proinsulin antibody
Overview
Overview
| Synonyms | Monoclonal Proinsulin antibody, Anti-Proinsulin antibody |
|---|---|
| Applications | ELISA, Immunoassays |
| Immunogen | Proinsulin antibody was raised in mouse using purified human proinsulin as the immunogen. |
| Assay Information | 10-I30G can be used in a sandwich immunoassay as a coating antibody in conjunction with 10-I30B as the conjugate antibody |
Specifications
| Host | Mouse |
|---|---|
| Clone | M12619PI1 |
| Isotype | IgG1 kappa |
| Method of Purification | Proinsulin antibody was purified by Protein A chromatography. |
| Form & Buffer | Supplied in PBS, pH 7.4, 0.1% sodium azide (NaN3) |
Storage & Safety
| Storage | Store at 4 Deg C |
|---|---|
| Biohazard Information | This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1%) as preservative. Although the amount of sodium azide is very small appropriat |
General Information
| Biological Significance | Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. Proinsulin is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized. It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin. |
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