Proinsulin antibody (10-P14B)

Mouse monoclonal Proinsulin antibody

Synonyms Monoclonal Proinsulin antibody, Anti-Proinsulin antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA, IHC
Immunogen Proinsulin antibody was raised in mouse using human proinsulin as the immunogen.
Assay Information 10-P14B can be used as the coating antibody with10-I30B as the conjugate antibody


Host Mouse
Clone M32237
Isotype IgG1 kappa
Method of Purification Proinsulin antibody was purified by chromatography on protein A Sepharose.
Form & Buffer Supplied as a liquid in PBS, with 0.1 % NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. Proinsulin is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized. It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin.

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