Proteasome 20S alpha 3 antibody (70R-13547)
Affinity purified Rabbit polyclonal Proteasome 20S alpha 3 antibody
Overview
Overview
| Synonyms | Polyclonal Proteasome 20S alpha 3 antibody, Anti-Proteasome 20S alpha 3 antibody, Proteasome S alpha 3-20, proteasome subunit C8 antibody, Proteasome S alpha 3-20 antibody, Proteasome S alpha 3 20, proteasome component C8 antibody, HC8 antibody, Proteasome 20S alpha 3, Proteasome S alpha 3 20 antibody, proteasome subunit alpha type-3 antibody, MGC32631 antibody, multicatalytic endopeptidase complex subunit C8 antibody, PSMA3 antibody, PSC3 antibody, MGC12306 antibody |
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| Cross Reactivity | Human |
| Applications | IHC-P, WB |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | Proteasome 20S alpha 3 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 28 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.36 mg/ml |
Usage & Assay Information
| Usage Recommendations | IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. |
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