Protein A (40nm Gold Colloid) (62R-A102GE)
Immunoglobulin-binding bacterial Protein A conjugated to 40nm colloidal gold in solution
Overview
Overview
| Synonyms | SpA protein, Protein A Gold colloid |
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Specifications
| Tag/Conjugate | Gold Colloid |
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| Form & Buffer | Supplied as a liquid with BSA/phosphate buffer, pH 7.4, and 0.1% NaN3 |
Storage & Safety
| Storage | Store at 2-8 deg C. PLEASE NOTE: Product expires 90 days from date of receipt. |
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General Information
| Biological Significance | is composed of five homologous Ig-binding domains that fold into a three-helix bundle. Each domain is able to bind proteins from many mammalian species, most notably IgGs. It binds the heavy chain within the Fc region of most immunoglobulins and also within the Fab region in the case of the human VH3 family. Through these interactions in serum, where IgG molecules are bound in the wrong orientation (in relation to normal antibody function), the bacteria disrupts opsonization and phagocytosis. |
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