Prothrombin factor II antibody (HRP) (60R-1044)
Sheep polyclonal Prothrombin factor II antibody (HRP) conjugated
Overview
Overview
| Synonyms | Polyclonal Prothrombin factor II antibody, Anti-Prothrombin factor II antibody, Prothrombin 2 antibody, Prothrombin factor 2 antibody, Coagulation factor 2 antibody, Coagulation factor II antibody, Prothrombin II antibody |
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| Applications | User optimized |
| Immunogen | Prothrombin factor II antibody (HRP) was raised in sheep using human Prothrombin purified from plasma as the immunogen. |
Specifications
| Host | Sheep |
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| Isotype | IgG |
| Tag/Conjugate | HRP |
| Form & Buffer | Supplied in liquid form in a buffered stabilizer solution containing 50% (v/v) glycerol. |
Storage & Safety
| Storage | Store at -10 to -20 deg C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. |
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General Information
| Biological Significance | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. |
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