PrP 27-30 antibody (20R-PG009)

Goat polyclonal PrP 27-30 antibody

Synonyms Polyclonal PrP 27-30 antibody, Anti-PrP 27-30 antibody, Prion protease-resistant protein 27-30 antibody
Specificity Human PrP
Cross Reactivity To be determined by end-user
Applications ELISA, IHC, WB
Immunogen PrP 27-30 antibody was raised in goat using a peptide; GQGGGTHSQWNKPSKPKTN, as the immunogen.

Specifications

Host Goat
Form & Buffer Supplied as liquid neat serum without preservative.

Usage & Assay Information

Usage Recommendations ELISA: > 1:1,500, IHC-P: > 1:300

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The prion protein is a large membrane protein that occurs normally in neurons of the human brain and is thought to be involved in synaptic transmission. In prion diseases, such as Creutzfeld-Jakob disease (CJD), Gerstmann-Straussler Scheinker syndrome (GSS), Fatal Familial Insomnia (FFI), Alpers Syndrome and Kuru, the normal cellular form of this protein (PrPc) is transformed into an altered protein when it comes into contact with an infectious prion protein (PrPsc) from another host. This altered PrPsc accumulates in cytoplasmic vesicles of diseased individuals forming lesions, vacuoles and amyloid deposits.

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Availability: In stock

Price: €277.55
Size: 250 ul
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