PSA/ACT complex protein (30-AP13)

Purified native Human PSA/ACT complex protein

Synonyms PSA-ACT complex protein, Prostate Specific Antigen/1-antichymotrypsin complex protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human plasma and seminal fluid
Grade & Purity > 96% pure
Molecular Weight 81 kDa
Form & Buffer 50mM PBS, pH 7.5, with 0.09% NaN3

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with hymotrypsin-like enzymatic activity, is monitored as increased levels can indicate prostatic neoplasia. PSA released into circulation is present as unbound, free PSA (fPSA) or bound to serum protease inhibitors, such as a1-antichymotrypsin (ACT) and a2-macroglobulin (A2M). Research indicates that immunoassays for serum levels of PSA alone cannot be relied on to distinguish prostate cancer from benign prostatic hyperplasia (BPH). Serum levels of PSA-ACT complex are reportedly higher in patients with prostate cancer than in those with BPH. As such, measuring the ratio of PSA-ACT to fPSA in patient samples is proving valuable in the differential diagnosis os prostate cancer.

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Availability: In stock

Price: €611.55
Size: 50 ug
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