PSAP antibody (70R-12559)

Affinity purified Rabbit polyclonal PSAP antibody

Synonyms Polyclonal PSAP antibody, Anti-PSAP antibody, sphingolipid activator protein-1 antibody, GLBA antibody, FLJ00245 antibody, SAP1 antibody, proactivator polypeptide antibody, prosaposin antibody, MGC110993 antibody, PSAP antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen PSAP antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 250 of PSAP

Images

Immunohistochemical staining using PSAP antibody (70R-12559)

Immunohistochemical staining of paraffin-embedded NCIN87 xenograft using PSAP antibody at a dilution of 1:500

Specifications

Host Rabbit
Isotype IgG
Method of Purification PSAP antibody was purified by antigen-affinity chromatography
Molecular Weight 58 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.97 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using PSAP antibody (70R-12559)</font></div>     | Immunohistochemical staining of paraffin-embedded NCIN87 xenograft using PSAP antibody at a dilution of 1:500
  • <div><font face=Calibri size=2>Western blot analysis using PSAP antibody (70R-12559)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Molt-4) using a 7.5 % SDS PAGE gel and PSAP antibody at a dilution of 1:2000

Availability: In stock

Price: €323.11
Size: 100 ul
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