Pseudolysin protein (lasB) (30R-3401)

Recombinant Pseudomonas aeruginosa Pseudolysin (lasB) protein

Synonyms Elastase Neutral metalloproteinase, Pseudomonas aeruginosa Pseudolysin ((strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) Elastase, Recombinant Pseudomonas aeruginosa Pseudolysin(lasB), Pseudolysin (Pseudomonas aeruginosa), Neutral metalloproteinase; PAE; Pseudolysin; Cleaved into the following chain: Pro-elastase
Species Bacterial
Protein Type Recombinant

Specifications

Residues Amino acids: 198-498 partial protein with N-terminal 6xHis-SUMO-tag.
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 49.12 kDa
Tag/Conjugate His-Sumo tag
Form & Buffer Lyophilized from aTris-based buffer

Storage & Safety

Storage Store at -20 deg Cshort term, -70 deg Clong term. Avoid repeated freeze thaw cycles.

General Information

Biological Significance Cleaves elastin, collagen, IgG, and several complement components. Involved in the pathogenesis of P.aeruginosa infections. This enzyme belongs to the peptidase family M4 (thermolysin family). Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects.
Sequence Information AEA GGPGGNQKIG KYTYGSDYGP LIVNDRCEMD DGNVITVDMN SSTDDSKTTP FRFACPTNTY KQVNGAYSPL NDAHFFGGVV FKLYRDWFGT SPLTHKLYMK VHYGRSVENA YWDGTAMLFG DGATMFYPLV SLDVAAHEVS HGFTEQNSGL IYRGQSGGMN EAFSDMAGEA AEFYMRGKND FLIGYDIKKG SGALRYMDQP SRDGRSIDNA SQYYNGIDVH HSSGVYNRAF YLLANSPGWD TRKAFEVFVD ANRYYWTATS NYNSGACGVI RSAQNRNYSA ADVTRAFSTV GVTCPSAL

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Availability: In stock

Price: €163.60
Size: 50 ug
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