PSMC6 antibody (70R-12798)

Affinity purified Rabbit polyclonal PSMC6 antibody

Synonyms Polyclonal PSMC6 antibody, Anti-PSMC6 antibody, conserved ATPase domain protein 44 antibody, proteasome 26S subunit ATPase 6 antibody, CADP44 antibody, PSMC-6, proteasome subunit p42 antibody, PSMC 6 antibody, PSMC-6 antibody, P44 antibody, PSMC6, 26S protease regulatory subunit 10B antibody, PSMC 6, 26S proteasome AAA-ATPase subunit RPT4 antibody, PSMC6 antibody, p42 antibody, SUG2 antibody, MGC12520 antibody
Cross Reactivity Human, Mouse
Applications ICC, IF, IHC-P, WB
Immunogen PSMC6 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 301 of PSMC6

Images

Western blot analysis using PSMC6 antibody (70R-12798)

Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10 % SDS PAGE gel and PSMC6 antibody at a dilution of 1:1000

Specifications

Host Rabbit
Isotype IgG
Method of Purification PSMC6 antibody was purified by antigen-affinity chromatography
Molecular Weight 46 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

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Images

  • <div><font face=Calibri size=2>Western blot analysis using PSMC6 antibody (70R-12798)</font></div>     | Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10 % SDS PAGE gel and PSMC6 antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Western blot analysis using PSMC6 antibody (70R-12798)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: 293T) using a 7.5 % SDS PAGE gel and PSMC6 antibody at a dilution of 1:500
  • <div><font face=Calibri size=2>Immunofluorescent staining using PSMC6 antibody (70R-12798)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PSMC6 antibody at 1:500 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using PSMC6 antibody (70R-12798)</font></div>     | Immunohistochemical staining of paraffin-embedded HeLa xenograft using PSMC6 antibody at a dilution of 1:500

Availability: In stock

Price: €323.11
Size: 100 ul
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