PUF60 antibody (70R-12639)
Affinity purified Rabbit polyclonal PUF60 antibody
Overview
Overview
| Synonyms | Polyclonal PUF60 antibody, Anti-PUF60 antibody, ro-binding protein 1 antibody, SIAHBP1 antibody, PUF-60 antibody, poly-U binding splicing factor PUF60 antibody, siah binding protein 1 antibody, FBP interacting repressor antibody, poly(U)-binding-splicing factor PUF60 antibody, Ro ribonucleoprotein-binding protein 1 antibody, roBP1 antibody, PUF60 antibody, PUF 60, RoBPI antibody, PUF60, siah-BP1 antibody, FIR antibody, FLJ31379 antibody, Ro ribonucleoprotein binding protein 1 antibody, PUF 60 antibody, PUF-60 |
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| Cross Reactivity | Human |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | PUF60 antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 523 of PUF60 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | PUF60 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 58 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.81 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. |
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