PYK2 antibody (10R-2149)

Mouse monoclonal PYK2 antibody

Synonyms Monoclonal PYK2 antibody, Anti-PYK2 antibody, Protein tyrosine kinase 2 beta antibody, PTK2B antibody, PKB antibody, PTK antibody, CAKB antibody, FAK2 antibody, FRNK antibody, PYK2, PYK 2, PYK-2, PYK 2 antibody, PYK-2 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen PYK2 antibody was raised in Mouse using a purified recombinant fragment of PYK2(aa815-997) expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using PYK2 antibody (10R-2149)

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 antibody.

Specifications

Host Mouse
Clone 5E2D5
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PYK2 is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.

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Images

  • Immunohistochemical staining using PYK2 antibody (10R-2149) | Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 antibody.
  • Western Blot analysis using PYK2 antibody (10R-2149) | Western Blot showing PYK2 antibody used against Raji (1), PMA induced THP-1 (2), Jurkat (3) and Ramos (4) cell lysate.

Availability: In stock

Price: €309.90
Size: 100 ul
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