RAB5A protein (30R-1120)
Purified recombinant Human RAB5A protein
|Synonyms||RABA-5 protein, RAB5A protein, RAB5 protein, RABA-5, member RAS oncogene family protein, RAB5A, RAB5A member RAS oncogene family protein, RABA 5, RABA 5 protein, RAS associated protein RAB5A protein, member RAS oncogene family RAB 5 protein, Ras related protein Rab 5A., RAB5A protein, Rab5a protein, RAB 5A protein|
Coomassie Blue stained SDS-PAGE of Rab5a protein (30R-1120)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-215 amino acids: MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN|
|Grade & Purity||> 95% pure|
|Molecular Weight||23 kDa ( 215 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||Rab5a is a member of RAS oncogene family. The small GTPase, Rab5a is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex. Recombinant human Rab5a was expressed in E. coli and purified by using conventional chromatography techniques.|
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