RAB6B protein (His tag) (80R-1676)
Purified recombinant Human RAB6B protein
|Synonyms||RABB 6 protein, member RAS oncogene family, RABB-6 protein, Ras-related protein Rab-6B protein, RAB6B, RAB6B protein, RABB-6, RABB 6|
Coomassie Blue stained SDS-PAGE of RAB6B protein (His tag) (80R-1676)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-208 amino acids: MGSSHHHHHH SSGLVPRGSH MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC|
|Grade & Purity||> 95% pure|
|Molecular Weight||25.6 kDa (228aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RAB6B, also known as ras-related protein Rab-6B, belongs to Rab6 family of the small GTPase superfamily. The Rab6 subfamily consists of three different isoforms: Rab6A, Rab6A' and Rab6B. Both Rab6A and Rab6A' are ubiquitously expressed whereas Rab6B is predominantly expressed in brain. Rab6 is a key regulator in the retrograde transfer from endosomes via the Golgi to the ER and may function in retrograde tansport in neuronal cells. Recombinant human RAB6B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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