RAMP2 antibody (70R-13201)

Affinity purified Rabbit polyclonal RAMP2 antibody

Synonyms Polyclonal RAMP2 antibody, Anti-RAMP2 antibody, RAMP2, RAMP 2, calcitonin receptor-like receptor activity modifying protein 2 antibody, CRLR activity-modifying protein 2 antibody, receptor (calcitonin) activity modifying protein 2 antibody, receptor activity modifying protein 2 antibody, receptor activity-modifying protein 2 antibody, receptor-activity-modifying protein 2 antibody, calcitonin-receptor-like receptor activity-modifying protein 2 antibody, RAMP-2 antibody, RAMP2 antibody, RAMP-2, RAMP 2 antibody
Cross Reactivity Human
Applications IHC-P, WB

Images

Immunohistochemical staining using RAMP2 antibody (70R-13201)

Immunohistochemical staining of paraffin-embedded SG xenograft using RAMP2 antibody at a dilution of 1:100

Specifications

Host Rabbit
Isotype IgG
Method of Purification RAMP2 antibody was purified by antigen-affinity chromatography
Molecular Weight 20 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor activity modifying proteins. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using RAMP2 antibody (70R-13201)</font></div>     | Immunohistochemical staining of paraffin-embedded SG xenograft using RAMP2 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using RAMP2 antibody (70R-13201)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A:MOLT4; B:Raji) using a 12 % SDS PAGE gel and RAMP2 antibody at a dilution of 1:1500

Availability: In stock

Price: €323.11
Size: 100 ul
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