Rantes protein (30R-1374)
Purified recombinant Human Rantes protein
|Synonyms||Small inducible cytokine subfamily A (Cys Cys) member 5., T cell specific protein p288 protein, Chemokine (C C motif) ligand 5 protein, D17S136E protein, SCYA5 protein, CCL 5 protein, TCP 228 protein, Chemokine CC Motif Ligand 5 protein, Regulated upon activation normally T expressed and presumably secreted protein, T cell specific RANTES protein protein, SIS delta protein, CCL5 protein, TCP228 protein, SISd protein, MGC17164 protein, SCYA 5 protein, Small inducible cytokine A5 Beta chemokine RANTES precursor protein, Small inducible cytokine A5 (RANTES) protein|
Coomassie Blue stained SDS-PAGE of Rantes protein (30R-1374)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||24-91 amino acids: MSPYSSDTTP CCFAYIARPL PRAHIKEYFY TSGKCSNPAV VFVTRKNRQV CANPEKKWVR EYINSLEMS|
|Grade & Purity||> 95% pure|
|Molecular Weight||7.9 kDa (69aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||Rantes, also known as CCL5, is the protein classified as a chemotactic cytokine or chemokine. This protein is a chemotactic for blood monocytes, memory T helper cells, eosinophils and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. Rantes also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also an HIV-suppressive factor released from CD8+ T cells. Recombinant RANTES protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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