RARalpha protein (His tag) (80R-1038)

Purified recombinant Human RARalpha protein

Synonyms RAR protein, Retinoic acid receptor alpha protein, NR1B1 protein, alpha isoform 1, Retinoic acid receptor protein, RAR alpha protein, Retinoic acid receptor protein, alpha isoform 1 protein, RARalpha protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of RARalpha protein (His tag) (80R-1038)

SDS-PAGE gel analysis of RARalpha protein (His tag) where the figure is annotated with amount of protein run on the gel.

Specifications

Residues 134-285 amino acids, 68-173 amino acids: MGSSHHHHHH SSGLVPRGSH MSEEIVPSPP SPPPLPRIYK PCFVCQDKSS GYHYGVSACE GCKGFFRRSI QKNMVYTCHR DKNCIINKVT RNRCQYCRLQ KCFEVGMSKE SVRNDRNKKK KEVPKPE
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 14 kDa (127 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris, pH 7.5, containing 0.1M NaCl, and 5mM beta-mercaptoethanol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor (RXR), which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT (NCOR2), and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.

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Images

  • SDS-PAGE analysis of RARalpha protein (His tag) (80R-1038) | SDS-PAGE gel analysis of RARalpha protein (His tag) where the figure is annotated with amount of protein run on the gel.

Availability: In stock

Price: €239.92
Size: 100 ug
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