RASSF1 antibody (70R-12540)
Affinity purified Rabbit polyclonal RASSF1 antibody
Overview
Overview
| Synonyms | Polyclonal RASSF1 antibody, Anti-RASSF1 antibody, RASSF 1 antibody, RASSF-1 antibody, ras association domain-containing protein 1 antibody, WUGSC:H_LUCA12.5 antibody, pancreas-specific ras association domain family 1 protein antibody, RASSF1, RDA32 antibody, RASSF-1, REH3P21 antibody, NORE2A antibody, cardiac-specific ras association domain family 1 protein antibody, RASSF1 antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, RASSF1A antibody, 123F2 antibody, tumor suppressor protein RDA32 antibody, RASSF 1 |
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| Cross Reactivity | Human |
| Applications | ICC, IF, WB |
| Immunogen | RASSF1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 50 and 344 of RASSF1 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | RASSF1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 39 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:200, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. |
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