RASSF1 antibody (70R-12540)

Affinity purified Rabbit polyclonal RASSF1 antibody

Synonyms Polyclonal RASSF1 antibody, Anti-RASSF1 antibody, RASSF 1 antibody, RASSF-1 antibody, ras association domain-containing protein 1 antibody, WUGSC:H_LUCA12.5 antibody, pancreas-specific ras association domain family 1 protein antibody, RASSF1, RDA32 antibody, RASSF-1, REH3P21 antibody, NORE2A antibody, cardiac-specific ras association domain family 1 protein antibody, RASSF1 antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, RASSF1A antibody, 123F2 antibody, tumor suppressor protein RDA32 antibody, RASSF 1
Cross Reactivity Human
Applications ICC, IF, WB
Immunogen RASSF1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 50 and 344 of RASSF1

Images

Immunofluorescent staining using RASSF1 antibody (70R-12540)

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RASSF1 antibody at 1:100 dilution.

Specifications

Host Rabbit
Isotype IgG
Method of Purification RASSF1 antibody was purified by antigen-affinity chromatography
Molecular Weight 39 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:200, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.

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Images

  • <div><font face=Calibri size=2>Immunofluorescent staining using RASSF1 antibody (70R-12540)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RASSF1 antibody at 1:100 dilution.
  • <div><font face=Calibri size=2>Western blot analysis using RASSF1 antibody (70R-12540)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A:293T) using a 12 % SDS PAGE gel and RASSF1 antibody at a dilution of 1:500

Availability: In stock

Price: €323.11
Size: 100 ul
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