RASSF1A protein (His tag) (80R-2593)
Purified recombinant RASSF1A protein
Overview
Overview
| Synonyms | RASSFA 1 protein, Ras association domain-containing protein 1 protein, RASSF1 protein, RASSF1A, RASSFA-1, RASSFA 1, RDA32 protein, 123F2 protein, NORE2A protein, REH3P21 protein, RASSFA-1 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of RASSF1A protein (His tag) (80R-2593)
SDS-PAGE gel analysis of RASSF1A protein (His tag) where the figure is annotated with amount of protein run on the gel.
Specifications
| Residues | 1-340 aa: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSGE PELIELRELA PAGRAGKGRT RLERANALRI ARGTACNPTR QLVPGRGHRF QPAGPATHTW CDLCGDFIWG VVRKGLQCAH CKFTCHYRCR ALVCLDCCGP RDLGWEPAVE RDTNVDEPVE WETPDLSQAE IEQKIKEYNA QINSNLFMSL NKDGSYTGFI KVQLKLVRPV SVPSSKKPPS LQDARRGPGR GTSVRRRTSF YLPKDAVKHL HVLSRTRARE VIEALLRKFL VVDDPRKFAL FERAERHGQV YLRKLLDDEQ PLRLRLLAGP SDKALSFVLK ENDSGEVNWD AFSMPELHNF LRILQREEEE HLRQILQKYS YCRQKIQEAL HACPLG |
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| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 42.9 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage, for long term storage aliquot and freeze at -20 deg C or -70 deg C |
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General Information
| Biological Significance | RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. |
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