Rat anti Mouse IgG3 (41R-1115)
Rat anti Mouse IgG3 secondary antibody
Overview
Overview
| Synonyms | Monoclonal Mouse IgG3, Anti-Mouse IgG3, Mouse Immunoglobulin G3 antibody, Mouse IgG3 antibody |
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| Applications | ELISA |
| Immunogen | Rat anti-Mouse IgG3 was raised in Rat using Mouse IgG3 as the immunogen. |
Specifications
| Host | Rat |
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| Clone | KT94 |
| Isotype | IgG2a |
| Method of Purification | Rat anti-Mouse IgG3 was purified using Protein G chromatography. |
| Form & Buffer | Supplied in PBS buffer containing 0.1% sodium azide as a preservative |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | ELISA: 1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C for 1 month. For long term storage aliquot and store at -20 deg C to -80 deg C. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains 0.1% sodium azide which is hazardous |
General Information
| Biological Significance | Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection. |
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