Rat Cyclooxyegenase 1 ELISA kit (55R-2260)

Cyclooxyegenase 1 ELISA kit for detection of Rat COX1 in serum, plasma and tissue homogenates

Synonyms Rat COX1 ELISA kit, Rat COX-1 ELISA kit, Rat Cyclooxyegenase-1 ELISA kit, RP11-542K23.6 ELISA kit, COX3 ELISA kit, PCOX1 ELISA, PGG/HS ELISA kit, PGHS-1 ELISA kit, PGHS1 ELISA kit, PHS1 ELISA, PTGHS ELISA kit, prostaglandin G/H synthase and cyclooxygenase|prostaglandin-endoperoxide synthase 1 ELISA
Applications ELISA
Assay Information This COX1 ELISA has a detection range of 7.8 pg/ml -500 pg/ml and sensitivity level of 1.95pg/ml. Serum, plasma and tissue homogenates may be used in this assay.

General Information

Biological Significance The cyclooxygenase isoenzymes, COX-1 and COX-2, catalyze a key step in the conversion of arachidonate to PGH2 in the formation of prostaglandins, thromboxane, and levuloglandins. Prostaglandinshavecritical functionsin numerous biologic processes, including the regulation of immune function, kidney development, reproductive biology, and gastrointestinal integrity.
Expression The COX1 enzyme is produced constitutively (i.e., gastric mucosa). This functional role for COX1 is consistent with its tissue expression patterns, where nearly all normal tissues were found to express COX1, including kidney, lung, stomach, duodenum, jejunum, ileum, colon, and cecum of rat, dog, Rhesus monkey, and human.
Implications in Disease Epidemiologic, animal, and human data indicate that NSAIDs, inhibitors of cyclooxygenase, are chemopreventive for colon cancer. NSAID use reduces risk for Alzheimer's Disease (AD), with users of these agents having as little as one half the risk of acquiring AD as those not taking NSAIDs.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Rat Cyclooxyegenase 1 ELISA Kit Protocol

Added: Jun 22, 2016

Download

Availability: In stock

Price: €768.92
Size: 1 kit
OR
Shipping
View Our Distributors