RBP4 protein (30R-1115)
Purified recombinant Human RBP4 protein
Overview
Overview
| Synonyms | RBP 4 protein, RBP-4, RBP-4 protein, Retinol binding protein 4 Plasma retinol binding protein 4 protein, RBP4 protein, prbp protein, Retinol binding protein 4 protein, , RBP4, Retinol binding protein 4 interstitial protein, RBP 4, PRO2222 protein, Retinol binding protein 4 plasma protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of RBP4 protein (30R-1115)
SDS-PAGE gel analysis of RBP4 protein where the figure is annotated with amount of protein run on the gel.
Specifications
| Residues | 19-201 amino acids: MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL |
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| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 21 kDa (184 aa), confirmed by MALDI-TOF. |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4. |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | < 1.0 EU per ug of protein (determined by LAL method) |
General Information
| Biological Significance | Retinol binding protein 4 (RBP4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. Recombinant human RBP4 was expressed in E. coli and purified by using conventional chromatography techniques. |
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