RELM alpha protein (30R-AR017)
Purified recombinant Murine RELM alpha protein
Overview
Overview
| Synonyms | Resistin-like alpha protein, Cysteine-rich secreted protein FIZZ1 protein |
|---|---|
| Species | Mouse |
| Protein Type | Binding Protein |
| Applications | User optimized |
Specifications
| Residues | Region of RELM alpha protein corresponding to amino acids MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 10.0 kDa |
| Form & Buffer | Lyophilized from 10mM tris, pH7.5, with 25mM NaCl. |
Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. |
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