RELM alpha protein (30R-AR017)

Purified recombinant Murine RELM alpha protein

Synonyms Resistin-like alpha protein, Cysteine-rich secreted protein FIZZ1 protein
Species Mouse
Protein Type Binding Protein
Applications User optimized

Specifications

Residues Region of RELM alpha protein corresponding to amino acids MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 10.0 kDa
Form & Buffer Lyophilized from 10mM tris, pH7.5, with 25mM NaCl.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel.

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