Renin protein (30-1209S)

Purified recombinant Human Renin protein

Synonyms Angiotensinogenase protein, REN protein, Recombinant Human Renin protein
Species Human
Protein Type Recombinant

Specifications

Residues Contains a C-terminal his tag
Expression System HEK293 cells
Grade & Purity > 95% pure
Method of Purification Purified by affinity chromatography
Molecular Weight 40 kDa
Tag/Conjugate His tag
Form & Buffer Supplied as a Lyophilized from 0.22 µm filtered 50 mM Tris-HCl and 50 mM NaCl, pH 8.0 with 5% trehalose.
Concentration > 100 ug/ml

Storage & Safety

Storage Aliquot and store at -70 deg C. Avoid repeated freeze thaw cycles.

General Information

Biological Significance Renin is an aspartyl protease that is specific for only one substrate, angiotensinogen that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.Prorenin is the precursor of renin andhas low level of enzymatic activity comparedto renin. This recombinant renin is produced from prorenin by proteolytic cleavage of a 43 amino acid N-terminal pro-segment using limited enzymatic digestion by immobilized trypsin and purified by affinity chromatography, resulting in >99% conversion toactive renin.

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Price: €485.07
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